Endocrine disrupting pollutants properties affecting their bio-activity, remediation, and detection

Valentina Dichiarante, Gabriella Cavallo and Pierangelo Metrangolo have recently published a review on "Endocrine disrupting pollutants properties affecting their bio-activity, remediation, and detection". The full paper can be found at the following link: Endocrine disrupting pollutants properties affecting their bio-activity, remediation, and detection.

 

Abstract. Endocrine disrupting chemicals (EDCs) are natural or synthetic substances able to mimic, interfere with or block endogenous hormones, thus disrupting the normal function of the endocrine system. Most of them are largely applied in agriculture and industry. As a result, humans are chronically exposed to mixtures of EDCs. Their adverse effect on human health may appear long after exposure, making it difficult to assess their full impact. Thus, understanding the molecular basis of recognition of suspected EDCs by their biological targets, is fundamental to get insight into their mechanism of action. This review will focus on the role of intermolecular interactions, specifically halogen and chalcogen bonds, in EDC recognition processes, offering an overview of the latest advances in the study of disruption mechanisms.

 

How to cite the article:
V. Dichiarante, G. Cavallo, P. Metrangolo
Current Opinion in Green and Sustainable Chemistry 2021, Volume 30, 2021, 100485
https://doi.org/10.1016/j.cogsc.2021.100485